EPA’s Legacy Of Toxic Waste: Agency And Industry Colluded Long Before Pruitt’s Arrival

The EPA's history of bending to the desires of industry, persecuting whistleblowers and burying its own research on the dangers of toxic chemicals


When Scott Pruitt took the helm of the Environmental Protection Agency in 2017, public health activists, environmentalists, and ordinary citizens, expressed outrage. How could a politician with close ties to the Koch-backed American Legislative Exchange Council (ALEC) be counted on to champion the Agency’s mandate? Why turn the EPA over to a lawyer who fought multiple lawsuits against it, and, who, as Attorney General of Oklahoma, disbanded that state’s Environmental Protection Unit? Less than two years later, Pruitt’s record as EPA head has only reinforced his detractors’ worst fears.

While Scott Pruitt’s tenure provokes almost daily controversy what remains less known is that the EPA has long been a compromised institution. In fact, decades before Pruitt arrived with his transparently anti-legislation agenda, EPA colluded with industry in ways that endanger public health and undermine its own mission.

I know this because in late 2017 my organization, the Bioscience Resource Project, collaborated with the Center for Media and Democracy to rescue and digitize The Poison Papers. These documents come mainly from the barn of longtime pesticide campaigner Carol Van Strum whose homesteading family and their neighbors were repeatedly sprayed in the 1970s by what turned out to be Agent Orange.

Aimed at Oregon forest weeds, these aerial sprayings instead killed her animals and sickened her children. So, Van Strum and her husband embarked on a decades-long investigation to uncover who knew what and when about Agent Orange. Their inquiry eventually broadened beyond Agent Orange and they ultimately amassed two and a half tons of eye-opening internal documents from the Agency and other sources. Collectively, The Poison Papers constitute an alarming portrait. Virtually from its inception in 1970, EPA has proactively overridden scientific evidence and sacrificed public safety for the benefit of the chemical industry.


Permethrin, often marketed as Nix, is a staple among insecticides. Approved by EPA in 1982 it is widely applied in agriculture and by homeowners. It is added to many consumer products, from carpets to clothing. Permethrin is also sold as an insect repellent for personal use. Given this ubiquity, no one would suspect that permethrin was approved for sale despite an internal EPA calculation that at legally allowable levels it would cause cancer in as much as 10% of the human population.

In a memo from the Poison Papers dated May 7, 1982, one of EPA’s most senior scientists, Adrian Gross, wrote bluntly to John Melone, Acting Director of EPA’s Hazards Evaluation Division, that: “the evidence is overwhelming that permethrin has a marked tumor-inducing or carcinogenic activity which is expressed in many different forms.”

Gross drew his conclusion from the seven long-term rat and mouse carcinogenicity studies on permethrin that were available to EPA at the time. Five of the seven were audited by the Agency and all showed clear evidence of scientific misconduct that disguised evidence of harm:

  • In one study, conducted by UK chemical company ICI, 160 mice were to be culled during the experiment and histologically examined. For reasons that no one at ICI or EPA could explain, nineteen mice were missing. As a highly trained toxicologist, Adrian Gross appreciated that such a breach of the study protocol invalidated any conclusion of safety.
  • Another study, conducted by Burroughs-Wellcome (also a manufacturer of permethrin), was equally plagued by mysterious omissions. In this case ten livers, 14 lungs and 131 pituitary glands that were supposed to be examined for pathology were missing. Once again, no explanation for the absence was forthcoming.
  • Gross also observed extraordinarily lax reporting of animal pathologies. He noted that: “… no professional pathologist was in attendance at the time the experimental animals were dissected after death in order to record grossly observable pathologic alterations in their carcasses and tissues.” Gross then noted how an EPA pathologist found more tumors than reported by one applicant, even with just a cursory examination of their tissue sections.

These and other serious lapses in the studies—which included fraudulent reporting—prompted Gross to write: “I cannot see how anyone in complete control of his senses could place any kind of reliability in any study conducted according to such practices” and later, “none of these seven studies can be regarded as having established that permethrin is ‘safe’ from a carcinogenic point of view.”

Just as disturbing, Gross showed EPA’s own evaluators systematically minimized or ignored evidence whenever studies showed that permethrin—even despite the irregularities—elevated cancers and other health dangers.

In August of the following year, Adrian Gross followed up with the Director of EPA’s Registration Division, Douglas Campt. It was in this memo that he made the ominous claim about permethrin’s cancer risk. Gross concluded that the proposed Acceptable Daily Intake (ADI) level of 0.05mg/Kg body weight per day of permethrin would result, depending on the extrapolation method, in an upper limit of cancer rates among the human population of between 1 and 10% from permethrin alone. “I should think that risks of cancer of this order… are unacceptable to any rational person,” he wrote.

Over Gross’s well-documented objections, EPA officials deemed permethrin safe. It was introduced to the market based on a final summary assessment written by Orville Paynter, the chief of EPA’s Toxicology Branch, and co-author Edwin Budd. This summary found no grounds for concern, concluding that “the risk of human oncogenic effects resulting from exposure to low levels of Permethrin is non existent or extremely low.”  


Gross, who died in 1992, was nothing if not dogged. In a separate memorandum to Jay Ellenberger of EPA’s Registration Division, dated June 18, 1981, concerning the pesticide oxamyl, Gross detailed the specifics of how EPA’s internal review procedures contrived to systematically discard clear evidence pointing to toxicological hazards.

Results damaging to a product were intensively and laboriously scrutinized by EPA reviewers until they were whittled down to findings more conducive to the chemical companies’ aims or disappeared altogether. This whittling took the form of successive rounds of internal evaluation, sometimes even necessitating special ad-hoc committees. In contrast, findings of lack of harm, even amid apparent testing fraud, received no such scrutiny.

George Bernard Shaw once wrote, “What a man believes may be ascertained, not from his creed, but from the assumptions on which he habitually acts.” Accordingly, our months spent combing through the Poison Papers force the conclusion that many EPA officials—and not just those who dealt with permethrin and oxamyl—believe that all scientific evidence of harm is an aberration and that their job is to dispute or downplay it. Across much of the Agency this has led to actions that have been similarly antithetical to a protective mission.

While Scott Pruitt’s ties to industry and his personal anti-regulation fervor have us duly worried, the Poison Papers show that the dysfunction goes far deeper than any one individual. EPA has operated largely, even entirely, in favor of the industry it is charged with regulating, yet it maintains the image of a public watchdog in the popular imagination.

That is because the biases are subtle. Couched in the language of science and rationality, the bending to industry can look reasonable on the surface; and because separate instances of bias often occur in EPA’s distinct bureaucratic jurisdictions the full extent of the co-optation is largely unknown, even to those within the system.   


If accurate diagnosis is the first step to a cure then three solutions readily present themselves.

The first is to empower and reward whistleblowers. Whistleblowers are enormous potential assets to society. If they can prove to the satisfaction of outside judges that the performance of their colleagues is seriously deficient or corrupt then whistleblowers should be formally and generously rewarded. Adrian Gross was sidelined and deprived of advancement, but others have had their careers and reputations jeopardized. In recent years, we’ve seen this with Cate Jenkins, an EPA chemist who resisted the Agency’s underestimation of the danger of dust at the 9/11 site.

The second solution originates with William Sanjour, another EPA whistleblower and former Branch Chief in its Hazardous Waste Division. While writing regulations Sanjour was specifically instructed to insert loopholes. The loophole instruction arose because EPA has no separation of powers between its rulemaking (i.e. legislative) functions and its enforcement functions. This is a conflict of responsibilities that we rightly do not tolerate elsewhere in government. The simple solution is to divide EPA into two agencies with one half being responsible only for enforcement. This solution is practiced in the UK where local municipalities enforce many food safety and other rules established nationally.

Thirdly, the leaders of each of these separate agencies should be responsible to Congress and not, as EPA’s Administrator now is, solely to the President. The reason is that presently EPA can only enforce environmental laws if the President acquiesces. It can never be a better environmental and health advocate than the person in the White House. With Trump in charge the danger of this should be immediately clear.

As Scott Pruitt’s conduct comes under scrutiny and if his position becomes increasingly tenuous, we may be lulled into a sense that EPA’s integrity is soon to be restored and that the mechanisms of justice are working in the public’s favor. But rescuing EPA and guaranteeing public safety is going to take more than firing one bad actor. It’s time to heed the lessons of The Poison Papers and make EPA the servant of the public, not the friend of industry.

[A version of this article was originally published at Salon.com.]

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Jonathan R Latham, PhD is co-founder and Executive Director of the Bioscience Resource Project and the Editor of Independent Science News. Dr Latham is also the Director of the Poison Papers project which publicizes documents of the chemical industry and its regulators.